i'll diss em. 50mg is a bs dose. could u possibly feel some effects at 200mg? sure. but think about this. i took lg sciences MMV3, their epiandro product. they have an "advanced' delivery system, i drank a cup of gfj i drank each dose, and grapefruit seed extract. so we have the cyclodextrin advanced delivery, a cup of grapefruit juice, grapefruit seed extract, and a dose of 300mg, and it was still pretty meh. i seriously doubt that 200 of this is gonna be a whole lot different.